In this issue, Strauss and Cohen 1 provide a cogent review of the phenomenology of negative symptoms transdiagnostically, illustrating the ways in which individuals across the psychotic disorder spectrum and those with other disorders (ie, bipolar disorder, depression, post-traumatic stress disorder) may experience seemingly similar negative symptoms. Negative symptoms can cause as much if not more disability and functional impairment than positive symptoms. However, individuals with psychosis can also experience “negative symptoms,” which involve impairments in hedonic and motivational function, and/or alterations in expressive affect. These are referred to as “positive symptoms,” as these are florid signs that are apparent to clinicians and family members. Psychotic disorders are associated with hallucinations, delusions, and disorganized speech and behavior. Here we highlight some of the emerging measures and paradigms that may help us to parse the nature and causes of negative symptoms, illustrating both the research approaches from which they emerge and the types of constructs that they can help elucidate.Īnhedonia, amotivation, assessment, negative symptoms, psychopathology, schizophrenia Introduction This approach is in line with the goals of the Research Diagnostic Criteria Initiative, which advocates understanding the nature of core dimensions of brain-behavior relationships transdiagnostically. Using such paradigms is particularly important if we wish to understand whether the causes are the same or different across disorders that may share surface features of negative symptoms. ![]() However, to better understand the mechanisms that may give rise to negative symptoms, we need tools and methods that can help distinguish among different potential contributing causes, as a means to develop more targeted intervention pathways. We have a number of excellent clinical tools available for assessing the presence and severity of negative symptoms. Clinicians and researchers have long known that one of the debilitating aspects of psychotic disorders is the presence of “negative symptoms,” which involve impairments in hedonic and motivational function, and/or alterations in expressive affect.
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